Posted by gilmourr on January 19, 2013, at 14:25:26
In reply to Re: Gillmore (again) » gilmourr, posted by SLS on January 19, 2013, at 13:02:20
> > I forget if I asked you SLS but what do you think about clonidine and Nardil?
>
> I think using clonodine would be a bad idea for two reasons:
>
> 1. Combined with Nardil, you might experience severe hypotension.
> 2. Clonodine is known to cause depression, even in healthy individuals.
>
> > Basically instead of lithium to lower norepinephrine?
>
> If you feel that you want to reduce NE activity, you could try prazosin. It has not produced dizziness for me in combination with Parnate except when I first started taking it. You could try propranalol or atenolol, but I am concerned with hypotension as a side effect.
>
> > I'm just trying to augment Nardil to get maybe a bit more serotonin, a bit less NE and the same D and GABA-T action.
>
> I know I have asked this of you before, but what is your rationale for concluding that you have too much NE?
>
>
> - ScottI believe I got too much NE because I had shivers, cold intolerance, urinary retention, constipation it even causes ejac issues. Which I believe are all adrenergic side effects.
shivers I think are related to hyperreflexia because I'd be sensitive to sounds and would jump a lot.
On Parnate which is even stronger on NE, I was like freezing cold, almost hypothermic.
So yeah, just based on that I think it's NE. As I don't get any of these side effects on SERT based meds.
And you might be wondering, well why do I want to go back on Nardil, well it's because my usual dose (the first two times I used it) I only had constipation at 45 mg which was getting better. At 60 mg I had all the previously listed side effects.
But the third time I used Nardil I had all the 60 mg side effects at 45 mg. Might be because I used some expired nardil, might be because my B6 levels were 4 times elevated, or maybe it was because I restarted it in 14 days. There was a sh*t tonne wrong and I need to test it agian.
poster:gilmourr
thread:1035661
URL: http://www.dr-bob.org/babble/20130112/msgs/1035821.html