Re: Does alcohol interfere with SSRI efficacy? » Prefect

Posted by phidippus on September 27, 2012, at 17:52:23

In reply to Does alcohol interfere with SSRI efficacy?, posted by Prefect on September 26, 2012, at 21:04:54

1. Potentiates the specific g-2L subunit of the GABA receptor, which activates the protein kinase C and causes sedation.
2. Inhibits the release of neurotransmitters - glutamate, and acetylcholine(ACH)
Also
1. Inhibits voltage gated Ca+ ion flux, which results in decreased endorphin release.
2. D2 Dopamine receptors are stimulated and endorphins are released, resulting in Euphoria. The exact mechanism of endorphin release is unknown.
3. Alcohol can temporarily raise mood enhancing chemical levels like those of serotonin, this is how it can improve mood, but in excess alcohol makes these serotonin levels fall and lowers mood, increasing depression. Taking alcohol with SSRIs can potentiate serotonin syndrome.
Eric

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Does alcohol interfere with SSRI efficacy? Prefect 9/26/12
Re: Does alcohol interfere with SSRI efficacy? Zyprexa 9/26/12
Re: Does alcohol interfere with SSRI efficacy? jane d 9/26/12
Re: Does alcohol interfere with SSRI efficacy? jono_in_adelaide 9/27/12
Re: Does alcohol interfere with SSRI efficacy? bleauberry 9/27/12
Re: Does alcohol interfere with SSRI efficacy? phillipa 9/27/12
Re: Does alcohol interfere with SSRI efficacy? » Prefect phidippus 9/27/12
Re: Does alcohol interfere with SSRI efficacy? » phidippus phillipa 9/27/12
Re: Does alcohol interfere with SSRI efficacy? jono_in_adelaide 9/28/12
Re: Does alcohol interfere with SSRI efficacy? » jono_in_adelaide ChicagoKat 10/4/12
Re: Does alcohol interfere with SSRI efficacy? » jono_in_adelaide ChicagoKat 10/4/12

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