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Saphris and Agranulocytosis - No risk-really?

Posted by Lou Pilder on February 28, 2012, at 19:51:39

In reply to Saphris and Agranulocytosis - No risk » Lou Pilder, posted by SLS on February 28, 2012, at 15:59:24

> > This is the aspect that I am attempting to explain, in that Clozaril caused agranulocytosis and then the whole class of those type of drugs is suspect.
>
> On what grounds?
>
> > Now I have shown a report where one took saphris and got agranulocytosis.
>
> No, you haven't.
>
> All you showed is that some private website says there was one instance reported to the FDA. No reference information was given to be able to corroborate this assertion. Medline/pubmed does not report a single case. Even if there were a single case, what does that say about the degree of danger possessed by Saphris. You have actually proven that Saphris is quite safe with respect to agranulocytosis.
>
> Okay.
>
> Enough about Saphris and agranulocytosis. If it occurs, you have proven that it is extremely rare.
>
>
> - Scott
>

Friends,
The issue here with saphris as to if it can cause agranulocytosis is not what I intended this thread to be about. I intended to show the chemical structure of the drug, where it came from and what it was used for and then the metamorphosis from the start to the ending up as saphris.
Now one important point is that the drug can cause blood diseases that could be fatal. The aspet of the drug causeing the type of blood disorder that Clozaril caused is mentioned as a warning in the FDA booklet for saphris as that drugs of that class could induce the same conditions. The theory is that the same catagory of drugs could cause the same things to cause death.
Now here is a link that states that saphris can cause agranulocytosis. It goes beyound that Clozaril could cause that because it is a drug like clozaril. It is in the review as you scroll down under adverse effects of saphris.
Since the drug is newer, there could be rapid ongoing changes in product liturature.
Now I intend to show the chemical structure of saphris and then one can decide if saphris is a new drug, or a new name for a knock-off of an old drug and then help people make a better decision as to take this drug or not with the information that I could give here so that lives could be saved, life ruining conditions could be avoided , addiction could be avoided, unless the rule of 3 applies.
Lou
here is the link to the review of saphris
http://www.pharmacistivist.com/2010/January_2010.shtml

 

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poster:Lou Pilder thread:1011122
URL: http://www.dr-bob.org/babble/20120221/msgs/1011946.html