Posted by SLS on February 7, 2012, at 5:09:29
In reply to Re: update, posted by g_g_g_unit on February 7, 2012, at 4:06:34
> ugh. I'm feeling so depressed and flat and apathetic this evening. this is bringing back bad memories of my last trial. I'm wondering if I should just increase the dose as fast as possible.
You might be "using up" your neurotransmitter stores as you experience a stimulant effect without first having established MAO inhibition.
People are variable in their tolerance of rapid titration of Parnate. Hypotension is usually the limiting side-effect.
Parnate usually does not help with more severe depressions until a dosage of 40 mg is reached. I take 80 mg. 60 mg is usually sufficient.
The following drugs, once considered high-risk, can be safely combined with a MAOI. The last three drugs can help with sleep.
methylphenidate
d-amphetamine
Wellbutrin
desipramine
nortriptyline
amitriptyline
trimipramine
doxepinThe real danger with mixing drugs with Parnate is serotonin rather than norepinephrine or dopamine. Any drug that inhibits the reuptake of serotonin can produce serotonin syndrome, a potentially fatal reaction. Geodon is the one AP that should probably be avoided.
Lithium, Lamictal, and Abilify make good adjuncts to Parnate in bipolar depression, and should not be a cause for concern for any doctor. I just so happen to be taking all of these. Each serves a different purpose. When I attempt to discontinue any one of these, I deteriorate.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1009314
URL: http://www.dr-bob.org/babble/20120202/msgs/1009539.html