Posted by NKP on April 20, 2011, at 13:41:08
According to Wikipedia:
"Flupentixol acts as an antagonist at various dopamine (D1-D5), serotonin (5-HT2), adrenaline (α1), and histamine (H1) receptors, without affecting the muscarinic acetylcholine receptors.
Its antipsychotic effects are likely caused by D2 and/or 5-HT2A antagonism, whereas its antidepressant effects at lower doses may be mediated by preferential D2/D3 autoreceptor blockade, resulting in increased postsynaptic activation."
(http://en.wikipedia.org/wiki/Fluanxol)
Since Fluanxol blocks the dopamine autoreceptor at lower doses, would this lessen the risk of tardive dysknesia?
poster:NKP
thread:983347
URL: http://www.dr-bob.org/babble/20110418/msgs/983347.html