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Re: Similar to Flibanserin

Posted by SLS on November 16, 2009, at 17:28:36

In reply to Similar to Flibanserin, posted by SheilaC on November 16, 2009, at 8:19:06

> According to the news today, Flibanserin, which was being studied as an AD may now be approved for female sexual dysfunction.
>
> I was wondering if there are other ADs or psych meds that have similar effects for a woman?


You might want to look at buspirone.


I would like to see flibanserin become available for whatever indication it can be approved for. Once that happens, I think it might be used as an augmenter of antidepressants to treat major depressive disorder, and perhaps generalized anxiety disorder. Flibanserin is a full agonist at the 5-HT1a receptor whereas buspirone and gepirone are only partial agonists. This might be what is responsible for any pronounced pro-sexual properties flibanserin might possess. Flibanserin also separates itself from buspirone and gepirone by acting as an antagonist of 5-HT2a receptors, something that might enhance its antidepressant and pro-sexual effects.


- Scott

 

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