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Re: Pristiq effects/combos?

Posted by West on November 6, 2009, at 15:56:07

In reply to Pristiq effects/combos?, posted by SheilaC on October 28, 2009, at 16:46:06

Hi Sheila,

There are lots of meds that are not SSRIs. It is prudent to differentiate between these and serotonergic meds at large. Keping this in mind, some examples of chemicals which raise serotonin but aren't SSRIs include:

Moclobemide (Reversible MAO-A inhibtor)

Nardil (Irreversible MAOI)

Parnate ('')

Buspirone (5-HT1A receptor partial agonist)

Tianeptine (accelerator/enhancer of 5-HT uptake)

Lu AA21004 (5-HT3 receptor antagonist, 5-HT1A receptor partial agonist, and 5-HT enhancer.Dose dependantly increases acetylcholine, dopamine, norepinephrine and 5-HT. See neorotransmitter.net for more details)

Trazodone (5-HT2A and 5-HT2C receptors antagonist. It increases 5-HT in the brain, though its metabolite, 1-m-chlorophenylpiperazine (m-CPP), acts as a 5-HT1A agonist decreasing 5-HT release.)

Nefazodone (potent antagonist at the 5-HT2 receptors)

Mirtazapine (5-HT2A/5-HT2C/5-HT3 receptor antagonist)



 

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