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Re: Trazadone and Parnate » Maxime

Posted by Sunbath on October 17, 2009, at 11:42:49

In reply to Re: Trazadone and Parnate » Sunbath, posted by Maxime on October 17, 2009, at 11:02:37

Hey Maxime, great you are getting it finally.
I take 175-200mg/night, but that is the extended release version so it's of course less than an equivalent of an immediate release one.

I'm no expert but I think you shouldn't take 200mg the very first night already, especially not when on Parnate?!
Also I don't know if you also experienced this, but some kind of a tolerance to trazodone's sedative effects builds up the first 1-2weeks when I begin taking it (again). During that time I have to gradually increase my dose until I reach a certain level where tolerance doesn't develop any further... I don't know if it's the same for you though..
Maybe to begin with 75 the first night and if you don't feel ready for sleep after 30min-1hr then take another 50-75mg would be safer?What do you think?

I also think it's very strange that we get tired during afternoon but are full of energy at night..
In current psychiatry vol 2002 they say:

"An altered diurnal sleep cycle is another
MAOI-related side effect. Some patients get
extremely drowsy in the late afternoon but then
may have insomnia at night.26 Attempts to alter
this odd cycle by changing the timing of adminis-
tration have generally not helped. We add a stim-
ulantpemoline (18.75 to 35.5 mg), d-ampheta-
mine (2.5 to 5 mg), methylphenidate (5 to 10 mg), or
modafinil (50 to 100 mg)either in the morning or during
afternoon sleepiness, with good effect and no hypertensive
crises. We supervise the effect on blood pressure of the first
few doses. Another helpful alternative has been to administer
trazodone at night to initiate sleep."

In another article I found they said that this effect wasn't completely understood.. maybe it's a mystery :D


Good luck Maxime, have a nice sleep tonight!!!


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