Posted by Alexanderfromdenmark on August 3, 2009, at 16:04:42
In reply to ANY EXPERIENCES WITH TESTOSTERONE FOR DEPRESSION?, posted by deprime82 on August 2, 2009, at 11:56:46
> hey!
>
> i have done 3 tests on global and bioavailable testosterone and at least the global testosterone was each time too low (although the test was conducted in the early morning).
>
> it was each time around 2.8 ng/ml of global testosterone (the bioavailable was okay)..
>
> at that time i was on 10mg lexapro and 5mg selegiline - maybe testosterone was suppressed a little by these meds, but in my opinion testosterone would be a starting-point for treatment of my depression (i am not treatment refractory, ssris always helped me very well, but motivation was always a problem).
>
> i have got no real libido problems, but i suffer from endogenous depression when i am not on ADs..
>
> beard growth isn't very dense.
> as i am only 24 years old, I wonder if the low testosterone could contribute to my depression or if the testo level is a result of 5 years of SSRI use...?
>
> any help would be appreciated..
>
> yours, dep82If you go to Meso Rx forum men's health.
you will find that many find a direct correlation between testosterone levels and depression.
Also search google for "mens hormonal health" and look up the depression section.Many have found that their depression was vanquished when they reached an optimal level of testosterone. Maybe so will you. I urge to to pursue the idea.
SSRI's detrimental efffect on testosterone levels:
PURPOSE: To evaluate endocrine profile and hypothalamic- pituitary- testis (HPT) axis in male depressed patients with selective serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction (SDF). MATERIALS AND METHODS: Eighty-six fertile depressed male patients with SSRI-induced SDF, aged 18 to 50 years, were enrolled in the study (group 1). Sixty-two age-matched depressed fertile patients who currently receive one of the SSRIs but without SDF (group 2), and 68 age-matched healthy fertile men who had never received a psychiatric diagnosis (group 3) served as controls. Pretreatment evaluation included history and physical examination and International Index of Erectile Function. Two blood samples were drawn from each subject at 20-minute intervals for the determination of the resting levels of the following hormones: luteinizing hormone (LH), follicle-stimulatin g hormone (FSH), testosterone, prolactin, and estradiol. The HPT axis was also assessed using
> the gonadotropin- releasing hormone test. RESULTS: The prevalence of hormonal abnormalities in groups 1, 2, and 3 were 83.7% (72), 51.6% (32), and 11.8% (7), respectively (P = 0.001 vs group 1 and 0.007 vs group 2). Compared with normal controls, the subjects taking SSRIs had significantly lower serum levels of LH, FSH, and testosterone. In addition, there were significantly decreased LH and FSH responses to gonadotropin- releasing hormone test in groups 1 and 2 compared with normal controls. Of patients in groups 1 and 2, 68 (79.1%) and 27 (43.5%) had elevated serum levels of prolactin (P = 0.0001 vs group 1 and 0.001 vs group 2). CONCLUSIONS: Most depressed subjects taking SSRIs with and without SDF had diminished HPT axis function. This should be replicated in further studies.
poster:Alexanderfromdenmark
thread:909857
URL: http://www.dr-bob.org/babble/20090801/msgs/910023.html