Posted by JadeKelly on March 16, 2009, at 22:50:29
In reply to Re: I want to switch from nortriptyline to desipramine » JadeKelly, posted by SLS on March 16, 2009, at 20:55:11
> > > I am not experiencing the improvement I expected. Depression is getting worse, not better. I have been on desipramine 300mg for only 12 days, so there is still something to hope for.
> > >
> > > I might have to go back to nortriptyline.
> > >
> > >
> > > - Scott
> >
> > Hey Scott,
> >
> > What would the response time be for someone who has never taken Desipramine? Are you still having insomnia?
> >
> > Remember, its not over yet. Its going to work and you're disappointed at how long its taking. I waited months, remember? ALL on faith. I still can't believe I made it. And you will too. Sorry but 12 days is a little early to start being negative. Hope it hits soon and complete. Ya just never know.
> >
> > ~Grasshopper
> >
>
>
> Hi Grasshopper :-)
>
> I misspoke. It has actually been 21 days that I am at the 300mg dosage. It is still too early to give up on it, though. However, I should see something more substantial soon if my drugs are optimized. I see my doctor tomorrow. I received the results from the blood test for 300mg. It came back at 191. The therapeutic range is between 100 - 300. I decided to take an extra 100mg of desipramine tonight to see if I were somehow just short of my therapeutic dosage. There is certainly enough room in blood levels to do this. I would feel noticeably better tomorrow if this were the case. If there is a night and day difference, I am going to have to explain my actions to my doctor. I'm just going to tell him that I couldn't wait anymore. 3 months of deterioration was enough.
>
>
>
> So anyway...
>
> I began to recover later in the day today. It is nothing great, but I feel better than I had been over the last few days.
>
> I have to admit that the last few days have been an emotional roller-coaster ride for me. I had suicidal thoughts creep in when I felt that my drugs had stopped working. I was despondent on top of being depressed. Not a good combination.
>
> Still moving forward...
>
>
> - Scott
>
>
Hi Scott,Glad your keeping in touch here. Its scary, to me anyway, when someone is very depressed and I can't reach them. Could you check in once a day here even just to say on a 1-10 (1 being suckiest) I'm a 3 or an 8. And add whatever else your up to sharing? Deal? Its selfish, I know...but what kind of mentor would you be if no-one knows you are okay? It is your calling.
So I'm a little confused. Is 100-300 Desipramine everyone's therapeutic range, or yours? If you don't respond to 191, but closer to 300, wouldn't it be a no-brainer as to why you are not responding? And why would you only give your therapeutic amount an overnight to work? You know better than I do. You need to think about other options as well. Thats what you told me, good to think ahead. Impress us. Everyone here loves you and even I do in that "your mean but your right" kinda way, haha. Hang in, okay? People care, you'll figure this out. Till tommorow then...let me know if you need more "stories".
~Grasshopper ;-)
poster:JadeKelly
thread:872122
URL: http://www.dr-bob.org/babble/20090313/msgs/885706.html