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Re: Nardil - may of upped daose to fast! » that_guy23

Posted by azalea on November 1, 2008, at 19:06:50

In reply to Nardil - may of upped daose to fast!, posted by that_guy23 on November 1, 2008, at 18:31:13

There are options for augmenting Nardil; T3 and Lithium are 2 options.

In addition, there are several ways to counteract the orthostatic hypotension. Here's what an article says: (Current Psychiatry Vol.1, No.6, June 2002, p.45) "Clinical significant hypotension is best managed via dosage adjustment. If that fails, add NaCl, 1 to 2 grams BID with increased fluids. If that doesn't work, administer fludrocortisone, 0.1 to 0.4 mg/day. If that fails, administer d-amphetamine, starting with 2.5 to 5 mg/day, and observe carefully for hypertension."

> I have ben on nardil for 8 weeks and 2 days. I think I thought because the euphoria was lessening, the drug was losing effect.
>
> I think incresed dosage far too soon far too high! I started at 15 mgs 1 week, upped to 45 mgs for 2 weeks, then at 75 for weeks 4 and 5, I had that euphoria, mood change, attiutude change, and more motivation. Not extreme , but it was noticible, even to me.
>
> Here is where me or my psychiatrist made a big mistake, I know I didn't ask for a dose this high considering i thought the highest wasat 90 mgs, she upped my dose for the 6th week to 105! I didn't know any difference! So I went on starting that dose, a day or 2 most I could feel major side effects. Orthostatic Hypotension, you can google it, it is a normal side efect of nardil,but I had it very bad. Along with the tiredness, all the time, and the other minor effects which I had already, don't know if they got worse.
>
> It got so bad I couldn't walk around or sometimes even stand staight up with out, getting dizzy eyes gradually lossing sight, which if they did would last like 30 sec - 1 min, and my ears would ring, or things got so loud, I felt weak,This is Orthostatic Hypotension in a nutshell. And most time's could lie down and fall asleep, almost immediately. I stuck 105 out for a week, like to do doses weekly, bi-weekly, etc. This way I can keep track easier.
>
> Then I called my psychiatrist to tell her I had to drop the dosage, to 90. I was supposed to see her in one week after this, my ride got cancelled and couldn't make it. I see her every 2 weeks as of now, and now at my time of need I had to wait 4 weeks.
>
> I stuck at 90, which was just as bad, for 13 days, and dropped back to 75 mg's, that was where I had the best results in the beginning. This was thursday 2 days ago.
>
> Since a few days of the big increase to 105 mgs,over 3 weeks now, I haven't been good. I'm really hoping that it's the way I was feeling, TERRIBLE, and not being able to do really anytihng, except minor excersice I started 8 weeks ago, that I never miss. I guess I'm coming around with the orthostatic hypotension, still there though, as wel as the minor side effects I had since almost starting.
>
> So now at just over 8 weeks at 75, i'm feeling depressed again. So theres no possitive change now, but there was.
>
> I would just like to know if I keep at this dose or even lower it, will this fix the problem eventually? If so will this mistake slow my recovery process?
>
> I had originaally had chose the drug for my SA, which I suffer from pretty bad. I am going to try and get somthing to counteract with it when I see her next thursday.
>
> Please anyone with any advice on this post, please tell me you've seen similar cases, or if not, just give me your input.
>
> I had, and still have high hopes for this drug, any drug that can be safely monterd to counteract with narl?
>
> Hope to hear from someone soon
>
> later


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poster:azalea thread:860267
URL: http://www.dr-bob.org/babble/20081027/msgs/860277.html