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Re: Didn't like Requip, for different reasons » Dopamine123

Posted by cactus on June 24, 2008, at 6:11:34

In reply to Didn't like Requip, posted by Dopamine123 on June 20, 2008, at 21:08:49

> I tried requip which has the same mechanism of action as mirapex. I found the cognitive side effects to be really bad. Requip tends to cause executive dysfunction because of reduced stimulation of the d1 receptors in the prefrontal cortex. The D2/D3 receptors are stimulated by the drug, but this actually reduces the amount of real dopamine in the synapse leading to a decreased activation of d1 receptors.
>
> So my verbal fluency (ability to talk) and concentrate took a huge hit when on the drug.
>
> My blog:
> http://brainstimulant.blogspot.com

wow, I had the opposite response. I posted a more detailed response up higher on the board. It was good and bad for me

 

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