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Re: modafinil and armodafinil, how do they differ? » undopaminergic

Posted by cactus on May 10, 2008, at 19:33:31

In reply to Re: modafinil and armodafinil, how do they differ????, posted by undopaminergic on May 9, 2008, at 19:43:56

> > I know they're very similar but what's the exact difference. I'm pretty sure armodafinil isn't available in australia but I'd like to know more about it, can anyone help explain it to me. I'm very happy with my modafinil but I'd just like to know.
> >
> > I'm asking in here because as soon as I start reading about chemical structures and isotopes etc, my brain just shuts down and shiny objects start getting my attention.
> >
>
> Modafinil is a so-called racemic mixture of equal amounts of two optical isomers, R-modafinil (armodafinil) and S-modafinil. See
> http://en.wikipedia.org/wiki/Enantiomer
>
> Often a substance is first marketed as the racemic mixture, and then the pharmacologically more active isomer is introduced as a patent-extender, usually with recommended doses that are half of those of the racemate.


Thanks undopaminergic for your reply but that was exactly what I was getting at. I don't understand a single sentence on that link, I've looked at it before.

Put it this way, is it like citalopram v's escitalopram. I know citalopram is weaker in concentration because it's slightly different. Which is the weaker between modafinil and armodafinil?

You're obviously well read/educated in chemistry and I'm not, could you explain it in a different way? The shiny objects caught my attention again and it was all too much to take in, or are you telling me that modafinil is the patent extender, which I do understand because that would explain the price.

Thanks C

 

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