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Re: And/or... » Phillipa

Posted by Racer on April 21, 2008, at 22:21:31

In reply to Re: And/or... » Racer, posted by Phillipa on April 21, 2008, at 12:14:47

>No wonder pdocs are starting doses lower than normal for those that are med sensitive.

I don't consider "med sensitive" to be a helpful phrase for me. If I had no sensitivity to medications, there would be no point in taking them, since they would have no effect. In my case, it has always required fairly high doses of medications to get benefits, and I have taken high doses of SSRIs and SNRIs. Right now, though, I am not willing to tolerate some of the adverse effects I have from them. It's not about being "med sensitive," it's about setting priorities in my life.

>But if I can tolerate a higher dose than you what do you think it means? That I am an SSRI responder or a nonresponder

It means that mileage varies. Nothing more, nothing less. It probably has nothing to do with whether or not you'd respond to an adequate trial of an SSRI at a therapeutic dose. It only means that your chemistry is different from mine, that you did not experience effects which bothered you at the dose you were taking, during the time you were taking it.

>I really don't know my knowledge isn't that understanding of neurotransmitters get that SSRI's affect the gut but for some reason don't with me?

Yes, they did affect your gut. You may not have had adverse GI effects, which some other people do experience on SSRIs, but there was an effect on your gut while you took them. That is because SSRIs affect the serotonin transport system when you take them -- whether or not that comes along with any adverse effects is a separate point.


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