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Re: Cymbalta(dose and HOW often take?Larry H,others? » Phillipa

Posted by Tony P on February 14, 2008, at 0:50:40

In reply to Re: Cymbalta(dose and HOW often take?Larry H,others? » Jay_Bravest_Face, posted by Phillipa on February 9, 2008, at 0:21:24

> Jay certainly not expert knowledge just having taken it and what I was told by the pdoc. [snip] ... this pdoc 20minutes first visit and said take 30mg one week then 60mg second week, then 90mg third week and then 120mg. I said but the manufacturer says that above 60mg doesn't make a difference. he said well I like the high dose so he scared me I couldn't tolerate 30mg and only stayed on it l0days that time. So I know psychologically there is a tie.

My old pdoc had been around a long time and I was more inclined to believe his experience when he said he had had good results with a few patients on 3x the mfgrs. recommended max dose, than the limited pre-market studies that said "no improvement found above xxxx dose". That being said, while I had no trouble with high doses of Lamictal (4-600 mg/day) I couldn't tolerate even normal doses of Effexor -- or at least I wasn't willing to go through a long adjustment period of crippling anxiety in the hope it would eventually work out.

So I guess I trust my own body first, an experienced pdoc second, and the manufacturer's "max effective dose" the least.


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