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Re: SSRI sex dysfunction - 5ht2a receptors - expla

Posted by cumulative on December 25, 2007, at 14:58:16

In reply to SSRI sex dysfunction - 5ht2a receptors - explain?, posted by Jimmyboy on December 23, 2007, at 0:23:38

5ht2a stimulation = dopamine antagonism

It's just a basically antagonistic relationship between the two neurotransmitter systems, although there are exceptions and with many SSRIs dopamine will be potentiated in certain parts of the brain.

Now, the definite involvement of dopamine and dopaminergics in hedonia, the pleasure response, goal-directed behavior (like sex) we all know and love, eh?


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