Posted by linkadge on November 14, 2007, at 16:00:19
In reply to Re: Cardiovascular toxicity of stimulants, posted by linkadge on November 14, 2007, at 15:56:38
One other unexplored issue about ritalin is this.
I just read a study that showed that a metabolite of ritalin was a potent 5-ht2b agonist.
The study (I will try to find) inferred that this may be of relavance to its calming action, as 5-ht2b agonists tend to supress locomotor activity.
Anyhow, 5-ht2b agonists can directly dammage the heart, ie pergolode type of mechanisms.
So, not only is it raising blood pressure, which is a risk for heart problems, it may also cause subtle dammage to heart valves (dending on the affinity of binding).
Linkadge
poster:linkadge
thread:794670
URL: http://www.dr-bob.org/babble/20071104/msgs/795082.html