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Re: Amisulpride..?? » marcus75

Posted by Amigan on September 27, 2007, at 18:52:41

In reply to Re: Amisulpride..??, posted by marcus75 on September 20, 2007, at 6:53:23

> I'd like to know what is the risk of developing tardive dyskinesia taking 50 mg/day, does anyone know this? For what I rembember, according to a study, at 100-200 mg the risk is about 1%. I am not sure whether the fact that at low doses it stimulates dopamine release, tardive dyskinesia is not possible. In fact the actual cause of TD is not known, there are various theories to explain it.

Highly unlikely! As you said, even at normal dosage, the risk is about 1%.
The exact mechanism that causes TD might not be known, but it is clear that it has to do with the post-synaptic antagonism of dopamine and (ami)sulpiride doesn't do that in low doses.


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