Posted by Jedi on August 16, 2007, at 12:59:20
In reply to Nardil and what? Best add-ons for TRD?, posted by stargazer2 on August 15, 2007, at 13:37:38
Stargazer,
Nortriptyline and other tricyclics that have very little effect on serotonin can be combined safely with Nardil. Caution is required. There is even some evidence that certain tricyclics can reduce the chance of a tyramine reaction.Gardenergirl has added lithium to Nardil with some success.
Take care,
JediHere are some references:
http://www.dr-bob.org/babble/20070604/msgs/761653.htmlA 3-year follow-up of a group of treatment-resistant depressed patients with a MAOI/tricyclic combination.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=7560546&ordinalpos=38&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumTreatment response of depressed outpatients unresponsive to both a tricyclic and a monoamine oxidase inhibitor antidepressant.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=8071301&ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumThe combined use of MAOIs and tricyclics.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&DbFrom=pubmed&Cmd=Link&LinkName=pubmed_pubmed&LinkReadableName=Related%20Articles&IdsFromResult=6376486&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus> After reading Michael's inspirational post about Nardil, I think I will give it a bit longer. I have been feeling quite useless and depressed ever since I had the hypertensive reaction about two weeks ago. It made me so scared I was convinced to go off it and try Celexa, Wellbutrin and Adderall again.
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> Now, I think I will try and add other medications to it. I know SLS has used Nortripyline, along with other meds. I have never tried Nortrip or any of the tricyclics so I'm tempted to do so. Also, I'm thinking about adding Lithium for some unknown reason, but alot has to do with other posts I have read recently.
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> Can Lithium be added to Nardil??? Anyone know????
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> Over the last week, I have only been on 30 Nardil and I have gotten more depressed. So on my own I added Lamictal, which caused me much cognitive decline at amounts above 100 mg, so I'm only taking 25 mg twice a day.
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> Can you tell I'm very desperate for finding something that can help me get out of where I am.
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> I'm waiting on endocrine labs that were drawn last week and I'm waiting for the nurse to follow up with me since she was away this week.
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> I see my pdoc on Friday and will have to tell him I've been experimenting on my own since waiting and doing nothing was excruciatingly difficult. (He has been away for 2 weeks)
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> I see no reason for being, no goals, no interest, no job, no friends, just my beloved pets who keep me company daily, but that isn't enough for me to say I am really living any worthwhile or meaningful life.
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> Why am I still here I often think, is there something that I'm supposed to be here for? I'm not sure but unless my husband reaches the breaking point with me, I will be OK with all this trial and error stuff. If I don't get well pretty soon, I will not be sure what I will do.
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> It's impossible to predict the future but there has to be more than what I have been going through the last 2-3 years.
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> I'm not sure what to do next...go back and try Celexa, stay with Nardil and add things to it, not sure at all, it is really not within my ability to sort this all out. I used to think I could understand what was going on with my meds and knowing what might work, but not anymore. I am stumped. That is what is really depressing. At least many other illnesses really have validated treatments but with depression there is only more wasted time. After so many years (20+), you have to start to lose hope. I don't have much time left to turn this around, I'm lost (sorry Michael) but that is my "uncensored" view of this situation.
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> Should I stay with Nardil(since 5/15, 3 mos exactly) and add to it? I'm so unsure of what to try next...Major symptoms are low self esteem, negativity, social anxiety, major anhedonia, inability to leave the house (3 or 4 days now). I don't know what to do anymore...
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> Can anyone tell me what I should do other than be patient and keep trying? I'm losing what little faith I have left, it is so debilitating and demeaning.
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> Stargazer
poster:Jedi
thread:776435
URL: http://www.dr-bob.org/babble/20070815/msgs/776632.html