Posted by Quintal on June 20, 2007, at 18:46:09
In reply to Re: weird parnate side effects after one week, posted by malcolm664 on June 20, 2007, at 16:09:04
>And why would you ever think that an MAOI is energizing? After all, it's supposed to diminish anxiety and drugs that do that are by nature always sedating
I think we've discussed this before - MAOIs are often stimulating (probably because they shore up noradrenaline and dopamine). Nardil is sedating mainly due to the action of the metabolite PEH (phenylethylidenehydrazine), which elevates levels of GABA in the caudate-putamen and nucleus accumbens. Nardil is unique among MAOIs in having this effect, and not all MAOIs are anxiolytic by any means.
Q
poster:Quintal
thread:764524
URL: http://www.dr-bob.org/babble/20070613/msgs/764583.html