Posted by Larry Hoover on February 19, 2007, at 15:18:53
In reply to A Parnate Canada vs. Parnate US Study!, posted by halcyondaze on February 19, 2007, at 14:46:11
> << http://ctr.gsk.co.uk/Summary/tranylcypromine/I_004.pdf >>
>
> Seems like Parnate US has a better bioavailability than Parnate Canada. I would LOVE to see this study with generics and UK brands.
>
> I never even saw this published; perhaps they declined to publish it?I think there would be no reason to publish it. The U.S. product had a larger standard deviation than did the Canadian product on every parameter except time to peak plasma concentration. If you take into account that variability, the advantage (if any) of the U.S. product is virtually negated. The only way I could imagine it would make a difference is if an American took to buying from a Canadian source, but I still don't know if it would matter very much.
Lar
poster:Larry Hoover
thread:734164
URL: http://www.dr-bob.org/babble/20070219/msgs/734186.html