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Re: Emsam vs. sublingual selegiline

Posted by Jakeman on May 27, 2006, at 22:12:38

In reply to Re: Emsam vs. sublingual selegiline, posted by Iansf on May 27, 2006, at 18:44:55

> > It's my understanding that with the patch there is less exposure to the amphetamine metabolites that are produced by selegeline. So it's my hope that insomnia may be less problematic with the patch. But I could be wrong.
> >
> > Jake
> >
> >
> Do you know why there might be less exposure to the amphetamine metabolites?

I was speaking in regard to the patch verus oral. Oral dosing has more first pass metabolism thus there's more exposure to the metabolites. I'm no expert, it's what I've gathered from reading the drug monograph at emsam.com


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