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Re: Loratadine for SSRI's sexual dysfunction

Posted by djmmm on May 17, 2006, at 7:30:31

In reply to Re: Loratadine for SSRI's sexual dysfunction » ed_uk, posted by Larry Hoover on May 16, 2006, at 16:34:20

> > Hi Lar
> >
> > I didn't think loratadine was active at serotonin receptors?
> >
> > Ed
>
> My language was somewhat ambiguous, I guess. Somehow, the loratadine effect reaches serotonergic receptors in the periphery, but I don't know the mechanism. Primary effect, secondary effect, I have no idea.
>
> Lar
>
>

I think you'll find that most antihistamines (first generation, and newer agents) have some serotonin activity... like SSRIs, histamine antagonists aren't necessarily that "selective" to histamine.


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