Posted by linkadge on May 2, 2006, at 18:31:07
In reply to Re: Animal models of psychiatric illness » linkadge, posted by zeugma on May 2, 2006, at 17:34:43
I think the animal models are valuble. I have to admit that some of the testing seems pretty sick to me. When I found out how they tested for potential new painkillers in animals I just about vomited. Thats not the way you treat something that moves and breaths.
Anyhow, so it goes.
>I agree. The disorder they seem most effective >for is OCD. dapoxetine, Lilly's new SSRI, is >going to be marketed for premature ejaculation, >and it may prove more efficacious for that >indication than for any mood disorder. Which is >frustrating, to say the least.
Thats exactly it. Zyprexa is probably a better weight gain pill than a antipsychotic. The best I could get from SSRI's was numb. Sure, they shut off certain circutry that I could do without, but they shut off a whole lot more.
Its hard to explain to a doctor how the drug makes you feel better, and yet *so* much worse all at the same time.
>Since we really have no clues as to the >underlying disorder in each person's case, >doctors use SSRI's as the most innocuous >choice, and the one that saves the labor of >diagnosis. I wish more thought went into >diagnosis, myself, but that study of 'teenage >pre-psychotics' shows me where diagnostic >skills go- into making money for pharma. It >makes me despair. It really does.
Its really pathetic. I just don't see how drug companies havn't changed their tactics yet. They don't think we can't see through these studies. Geez, I hope they've got represititives reading these boards. I don't know how some of these drug companies live with themselves. A good company would require all of its workers and drug reps to ingest the drug they push for 3 weeks and after that decide what is, and what is not an appropriate application.>I would be curious to know why amineptine is a >more effective AD than Ritalin, if it is. Just >like I am curious as to why atomoxetine is less >of an AD than desipramine, if it really is.
Some studies have found positive application of ritalin in depression:
http://biopsychiatry.com/methdep.htm
Yeah. I personally found that ritalin was an effective antidepresant. I had no compulsion to increase the dose. I found it helped my anhedonia, and I was able to get pleausure out of things I enjoyed doing, like playing the piano.
But you're right, it is strange that two drugs with similar mehanisms don't work the same.
Linkadge
poster:linkadge
thread:638491
URL: http://www.dr-bob.org/babble/20060429/msgs/639378.html