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Re: Klono depressing. Need long benzo not depressi » yxibow

Posted by ed_uk on April 27, 2006, at 16:19:46

In reply to Re: Klono depressing. Need long benzo not depressi » valene, posted by yxibow on April 26, 2006, at 19:30:08

Hi Yxi,

Flunitrazepam (Rohypnol) is a long-acting hypnotic. Its effects tend to persist the following morning. Triazolam (Halcion), as you said, has a short duration of action.

I did some research RE the metabolism of diazepam (Valium). It turns out that temazepam (a metabolite of diazepam) does not contribute significantly to the clinical effects of diazepam, since it is excreted at approximately the same rate as it is generated, and is therefore almost undetectable in the blood. Desmethyldiazepam is the only metabolite of diazepam which is clinically important.

Kind regards

Ed


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