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Re: Cymbalta - how much?

Posted by SLS on April 15, 2006, at 7:20:10

In reply to Cymbalta - how much?, posted by ben on April 15, 2006, at 4:32:32

> Hi
> Does Cymbalta have a dose related effectivness like Effexor? I am on 60 mg and wanted to know where you have found your effective dose.
>
> ben

I don't know if Cymbalta has the same sort of biphasic response pattern as Effexor. The ratio of concentrations necessary to inhibit the reuptake of serotonin versus norepinephrine are closer to 1:1 with Cymbalta.

I think it is reasonable to use 120mg as the maximum dosage. This dosage was used in quite a few of the investigative clinical trials. However, you really should give the 60mg at least four weeks before making any decisions.

Good luck.


- Scott

 

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