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Re: Opiate receptors - dopamine receptors » MARTY

Posted by SLS on March 25, 2006, at 22:53:02

In reply to Opiate receptors, posted by MARTY on March 25, 2006, at 21:14:51

>
> Hi Tepiaca --
>
> From what I`ve read some time ago, Opiate receptors are the most important receptors related to alchool rewarding effects.
>
> Alchoolic are sometime prescribe some Opiate receptor antagonist, like altrexone and Amperozide. Those reduces the effects/pleasure of the person who drink, resulting in reducing significally their alchool craving.
>
> Maybe someone on the forum had tried those and may want to share their experience with us...
>
> Hope you're well,
> Marty


I don't know via what mechanism alcohol activates the opioid system. Ultimately, it is the increased release of dopamine in the limbic system that produces the experience of reward. I'm not sure scientists are entirely clear on how alcohol works.

I found these instructive:

http://opioids.com/abstract/opdopalc.html

http://www.biopsychiatry.com/alcdepop.htm


- Scott

 

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