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Re: Trifluoperazine (Stelazine) and opioid tolerance » med_empowered

Posted by ed_uk on February 18, 2006, at 14:56:17

In reply to Re: Trifluoperazine (Stelazine) and opioid tolerance, posted by med_empowered on February 18, 2006, at 13:47:30

Hi Med

>I'd hate to be "treated" for addiction with Stelazine

Me too! I did think the article was interesting though.

>Are there any non-phenothiazine anti-emetic drugs?

Yes, there are many........

Domperidone (Motilium) - a selective D2 antagonist which doesn't cross the blood brain barrier. As a result, extrapyramidal side effects are very uncommon. Domperidone is not available in the US.

Metoclopramine (Reglan, Maxolon) - a drug related to the antipsychotics sulpiride and amisulpride.

Ondansetron (Zofran) and granisetron (Kytril). These drugs act at 5-HT3 receptors and are very useful for chemotherapy-induced nausea and vomiting.

Cyclizine (Valoid, Marezine) - an antihistamine and anticholinergic.

There are many more.......

Kind regards

Ed


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