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Re: Metyrapone - Has anyone tried this?

Posted by blueberry on February 2, 2006, at 5:22:05

In reply to Metyrapone - Has anyone tried this?, posted by SLS on February 1, 2006, at 19:25:33

I'm puzzled by the prospect of inhibiting cortisol synthesis. The reason is that cortisol is frequently way low in people with mood disorders. Elevated cortisol levels are rare. All this according to my doctor anyway, who specializes in combining psychiatric meds and nutrional support strategies.

Cortisol is indeed elevated early in the disease or condition. But that is short lived. The adrenal glands become exhausted, give up, and then cortisol levels drop off the charts and are unable to recover on their own. That's how it was explained to me anyway.

Low cortisol or inappropriate ratios of cortisol to dhea often explain things when meds don't work well, or have amplified side effects, or produce paradoxical or quirky results. According to my doctor. I have no personal opinions on it.

I'm an amateur when it comes to hormones, but from most things I have read and from what my doctor sees in her practice, nearly all psych patients need cortisol support, not cortisol inhibition.

So I am puzzled.


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URL: http://www.dr-bob.org/babble/20060129/msgs/605375.html