Posted by Larry Hoover on December 9, 2005, at 12:56:10
In reply to Re: Entering study vs symptoms, posted by Cairo on December 9, 2005, at 12:29:29
I only feel able to address some specific points, so I've snipped heavily.
> I am considering entering a study for the use of pregabalin in Fibromyalgia. It would be double blind and I would need to go off all meds for pain and sleep.
Right there, that's a huge decision, isn't it?
> my pdoc won't prescribe pregabalin off label for anxiety or something outside his area of expertise (the Neurontin lawsuits scare him - fair enough).
The FDA approval was for neuropathic pain and neuralgia. I'm not clear on why you would need an off-label prescription, given fibromyalgia as a diagnosis.
> Would it be crazy to go off all meds for this trial of pregabalin which I may or may not get and may or may not work?
I do think so. Adding it to your present cocktail seems to be a far wiser decision, though I accept that you are having difficulty getting a doctor to do so.
> It it's not advisable to not treat the symptoms, then what other medication(s) would you suggest?
>
> Oh, the quandry, the decisions!
>
> Thanks for any insights. My physician husband is just as stumped as I am that most meds don't work for me.
>
> CairoYour husband is a physician? Can he not write the script for you?
I'm using Lyrica, and I tolerate it much better than I did Neurontin. It's helping, but nortriptyline is doing a big chunk of the work (proven by trying to reduce the dose). The idea of going off everything , and having a 50% chance of staying on nothing for three months, doesn't provide much incentive, as I see it.
Lar
poster:Larry Hoover
thread:587337
URL: http://www.dr-bob.org/babble/20051203/msgs/587344.html