Posted by linkadge on December 1, 2005, at 16:10:35
In reply to Re: Linkadge » linkadge, posted by Jedi on December 1, 2005, at 0:02:46
Thats it. Long term antidepressant sucess may be related to neurogenesis.
But neurogenesis can be facilitated through many different pathways. For instance, NMDA antagonists promote neurogenesis.
Reducing levels of stress hormones also has a very strong impact on the rate and survival of proliferating hippocampal neurons. Tianaptine for instance has been shown to reduce HPA axis reactivity. In doing so it may have a favorable impact on neurogenesis.
All I am saying is that, while we study the mechansims for their effect, we need to also study the mechanisms for their failures (poop out etc)
Linkadge
poster:linkadge
thread:582599
URL: http://www.dr-bob.org/babble/20051126/msgs/584257.html