Posted by Chairman_MAO on November 25, 2005, at 12:45:28
In reply to Studies on long term use of SSRI's, posted by law663 on November 25, 2005, at 12:30:13
Taking a D2 agonist (think: pituitary) initially completely reversed my sexual dysfunction from buprenorphine+phenelzine. The effect went away, and it has never worked again, even at doses used by end-stage Parkinson's patients. I always like to mention that even at 8mg/day cabergoline had no detectable side effects in me.
Taking testosterone propionate ~250mg/wk has eliminated any trace of drug-induced sexual dysfunction. This suggests that buprenorphine+phenelzine together many have a testosterone-lowering effect and/or some other deletrious hormonal effect. One study in buprenorphine maintained healthy, young male heroin addicts showed no lowering of T at 16mg/day, but in combination with phenelzine this may not be the case ...
Given that many people on buprenorphine also take serotonergic psych meds, this warrants further investigation.
poster:Chairman_MAO
thread:582087
URL: http://www.dr-bob.org/babble/20051119/msgs/582090.html