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Re: Remeron is the same than Tolvon ??

Posted by SLS on November 11, 2005, at 7:22:45

In reply to Re: Remeron is the same than Tolvon ?? » Tepiaca, posted by Larry Hoover on November 10, 2005, at 22:59:34

> >
> > Hello, is Tolvon and Remeron the same med
> > only with 2 different comercial names???
> >
> > Thanks !
>
> No. Tolvon is mianserin. Remeron is mirtazapine, which is the 6-aza-derivative of mianserin.
>
> Remeron is "improved" Tolvon. They are not the same med.

Although there is great overlap in the pharmacology of these two drugs, Remeron has an additional effect on serotonin (5-HT) receptors.


Tolvon (mianserin):

NE alpha-2 antagonist
H1 antagonist
5-HT2 antagonist

Remeron (mirtazapine):

NE alpha-2 antagonist
H1 antagonist
5-HT2 antagonist
5-HT3 antagonist


Drugs usually do things other than what science recognizes and lists as important. Sometimes, just knowing that the chemical derivation of two drugs are different, as Larry indicates, is enough reason to try both drugs. Even if these two drugs looked the same to scientists, they would not necessary look the same to the brain. I agree with Larry in saying that Remeron, for the average person, is an improvement over Tolvon. However, there are probably people who respond better to Tolvon than Remeron. For me, I would choose Remeron first.


- Scott

 

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