Posted by tecknohed on August 5, 2005, at 18:18:56
In reply to Oh yay, another single-isomer drug launched in UK, posted by ed_uk on August 5, 2005, at 17:31:14
> It's a shame that the drug companies and spending so much time developing single-isomer drugs (think Lexapro $$$) rather than actually making the effort to develop innovative products.
>
> Dexibuprofen (Seractil) is now available in the UK. Dexibuprofen is the active isomer of ibuprofen.
>
> Seractil
>
> Composition: Dexibuprofen.
> Presentation: Film-coated tablets.
> Class: Anti-inflammatory and antirheumatic product.
> Indications: Symptomatic treatment for the relief of pain and inflammation associated with osteoarthritis or other forms of mild to moderate pain such as muscular-skeletal pain or dental pain. Acute symptomatic treatment of pain during menstrual bleeding.
> Dosage: 600 to 900mg daily, divided in up to three single doses. Maximum single dose 400mg.
> Precautions: Care is recommended in conditions that predispose patients to the gastrointestinal adverse effects of NSAIDs, and in elderly patients. In the rare instances where gastrointestinal bleeding or ulceration occurs, dexibuprofen should be discontinued immediately. In the treatment of patients with heart failure, hypertension, renal or hepatic disease, especially during concomitant diuretic treatment, the risk of fluid retention and a deterioration in renal function must be taken into account. See SPC.
> Contraindications: Include patients in whom substances with a similar action precipitate attacks of asthma, bronchospasm, acute rhinitis or cause nasal polyps, urticaria or angioneurotic oedema. Patients with gastrointestinal ulcers, bleeding disorders, Crohn’s disease, active ulcerative colitis, heart failure, severe renal dysfunction or severely impaired hepatic function. See SPC.
> Side effects: Most common are gastrointestinal. See SPC.
> Legal category: P*M.
> Net price: 300mg 60 £9.47, 400mg 60 £9.97.
>
> ~Ed
>LOL! Seems like the warnings and side effects are no different to standard Ibuprefen! Just like Escitalopram!
poster:tecknohed
thread:537977
URL: http://www.dr-bob.org/babble/20050803/msgs/538006.html