Posted by FredPotter on August 4, 2005, at 22:03:34
My psychiatrist thinks SSRIs work, although they may need augmentation, in my case with lithium and Zyprexa. Also he says there is no evidence that poop-out exists. Although the evidence presented on this board tends to be negative, understandably, the picture I get is that it's not clear that SSRIs work at all or if they do they often as not poop out.
I read once that scientists were working on placebos that gave side effects only, so subjects would not be able to twig what they were on. If this were done we could easily get the picture that SSRIs indeed do not work.
Given that clinical trials are quite short, the placebo response, although this is known to fade with time, could still be active at the end of the trial. Perhaps it's true that poop-out is actually a fading placebo response.
Fred
poster:FredPotter
thread:537656
URL: http://www.dr-bob.org/babble/20050803/msgs/537656.html