Posted by SLS on April 13, 2005, at 7:11:56
In reply to Re: Discontinuation-induced refractoriness: Remeron, posted by Jane9 on April 13, 2005, at 2:37:05
> I had only been taking the Remeron for 3 or 4 days, at a very small dose - I think it was 7.5mg, as the 15 mg. gave me nightmares the first night. Within a day I was "like a new person" - I had never had such success in 15 years of different ADs. After stopping, I started it again after just a week or so, to no effect (no side effects anymore either, interestingly). Also tried greater doses at later times to no effect.
>
> Effexor produced very bad side effects. I am now starting on lithium for the first time, to be combined with Remeron -does anyone know whether the order I take these two meds (or starting them both at the same time) makes a difference? Thanks everyone for your feedback.
>
>I doubt your system has become refractory to Remeron after a few days' exposure to it. Your "blip" improvement is not rare and sometimes happens withing the first 3 days of beginning a new drug. It usually doesn't last for more than a day or two. The true response occurs much later, at least two weeks after beginning treatment. You might have "tickled" the brain with Remeron.
These blip responses are often a good prognosis for later response.I don't think it matters what order you start the two drugs (Remeron and lithium). It's a great question, though. If it were me, I would probably try the Remeron as monotherapy first and add the lithium later on if you don't respond.
How much lithium was your doctor talking about having you take?
- Scott
poster:SLS
thread:483184
URL: http://www.dr-bob.org/babble/20050413/msgs/483635.html