Posted by ed_uk on March 5, 2005, at 10:54:21
In reply to Re: Does Norepinephrine cause anxiety?, posted by SLS on March 5, 2005, at 7:53:20
Hi Scott,
>When treating depression, desipramine, a selective NE reuptake inhibitor, can be anxiolytic.
Yes, this is true. Desipramine can be useful in panic disorder as well.
As you said earlier, no one really understands the mechanism of action of Wellbutrin. No one knows why Wellbutrin seems to cause anxiety for so many people, it might have nothing at all to do with norepinephrine. People often call Wellbutrin 'noradrenergic' or 'dopaminergic' but it is only a weak uptake inhibitor of norepinephrine and it's effect on dopamine uptake is so small that it may be insignificant. It's possible that the mechanism of action of Wellbutrin has little to do with either norepinephrine or dopamine. Alternatively, it could be affecting these amines in as yet unidentified ways.
Ed.
poster:ed_uk
thread:466710
URL: http://www.dr-bob.org/babble/20050304/msgs/466933.html