Posted by willyee on March 4, 2005, at 14:39:36
In reply to Re: Parnate: 2 week progress report, posted by Optimist on March 4, 2005, at 6:45:40
> > I take 70 mg daily.....i try to take less whenever possable.But yess if i have a therputic response i will take 20 mg,if otherwise i over amp myself.
> >
> > I know this sounds wierd,but i have been on it close to 5 years,and im very familiar with its onset.I did take it at a consistent dose and time my first year or two,but i find it more effective if listen to how im feeling.
> >
> > This of course is not somethig id advise anyone to do,especialy a person just on it.One example is if i am not having any response,ill begin to take 40 mg doses,in a day or two usualy ill achieve a therputic response,if i stay at this high dosage it will turn to depression and make me tired,so when i hit the range for me it is best to begin to lower it back,again this is only after very exstensive self montering of my reaction to dosages,which i achieved through years of familiarility with the med.
>
> I know you've had some problems lately with Parnate. Could it be possible your changing the doses around often may be effecting it's AD response? I think there is a difference between the MAO inhibition and stimulant effects time wise. After increasing the dosage, the stimulant effects are almost immediate whereas the MAOi AD response may take up to 8 weeks or so to max out. Could it be you're over-relying on the stimulant effect rather than MAO inhibition? Just a thought...
>
> Brian
Thats a logical thought....i have tried to take a specific dose at a specific time,and i simply cant tolerate it,depression worsens deeply.I actualy get either a stimulant effect,or a depressive one,what i aim for is the anti depressant effect which it once gave.
What you said is 100 percent accurate,but i have already been through the initial 8 week build up for Maoi effect oh 3 years ago.What i think might be the case is just how my body is absorbing the medication,via what i ate for the day,etc....
Klonopin as needed for example,i havent had to up a dose of that ever,the same dose does the same thing,unfortunatly this is not true with parnate,i feel sometimes its either going right through me,or its worsening the depression,and right when i cant take no more the med will work,its frustrating,but it is the only med effective,so as it stands now its either that or off meds altogther,and im simply not ready for that yet.
Nice to hear from other people who use this med though,other than here its a very rare thing to accomplish.
poster:willyee
thread:460810
URL: http://www.dr-bob.org/babble/20050304/msgs/466519.html