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Re: meds for agitated depression? » Spriggy

Posted by Ritch on February 5, 2005, at 12:41:53

In reply to meds for agitated depression?, posted by Spriggy on February 5, 2005, at 10:56:33

> I don't know if the term agitated depression or hypomania fits here.
>
> I've been extremely restless in my mind, uncomfortable and also extremely depressed. I can not take SSRI's- they make me worse. This is my doctor's conclusion after seeing me go from functioning but a little anxiety THEN (with Lexapro) utterly depressed and unable to function.
>
> What would be a good choice for me? I have some Wellbutrin XL that was prescribed but am terrifie to even try it again ( i took it for 2 days).
>
> I am wondering if I should ask for a mood stabilizer with the Wellbutrin.
>
> I am beginning to realize I have no choice any longer but to be on some type of medicine.
>
> I have two young children, a husband, a ministry, and am finding myself getting worse and worse.
>
> I've done ALL the natural stuff; I exercise 50 minutes a day, eat well, get enough sleep, tried St. John's Wort, Sam-E, and 5 h-tp.
>
> I take a good multivitamin and also Magnesium.
>
> Any ideas?

The WB might be really agitating for you. I'd give a tricyclic a shot. Nortriptyline is generally one of the most tolerable TCA's. It isn't real sedative or real activating. If you've got really bad insomnia you might want to use amitriptyline instead. Another idea is a combo of amitripytline + chlordiazepoxide (it used to be called Limbitrol-don't know if they still make it or not). When I first saw pdoc long ago for an agitated depression (which was probably a mixed bipolar state) they used Limbitrol (25mg AMI + 10mg CDP) + Doxepin 75mg (another TCA) at bedtime and it clobbered it pretty good. I also started lithium at the same time. If a different class of AD like a TCA boomerangs on you and makes you worse, then I would consider bipolar as the root cause. Hope this helps...


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