Posted by Lindsay Rae on January 25, 2005, at 20:18:16
In reply to Thanx you all for your help!!! (nm), posted by neo on January 25, 2005, at 18:22:12
I am facing the same problem and have switched to Valium. However, these are the reasons I have found out that it is not doing the trick the way Xanax has for me:
These belong to the benzodiazepine family of drugs. They all bind to the GABA receptor complex and make it easier for GABA to open the receptor's chloride ion channel, hyperpolarizing the neuron, making it less excitable and less likely to fire. Benzodiazepines are used as sedative/huypnotics (sleeping pills), anti-anxiety meds (anxiolytics), anti-panic agents, and anticonvulsants (anti-epileptics). The primary differences between all benzodiazepines are in their pharmacokinetic properties (their absorption, distribution, metabolism and excretion).
V = Valium (diazepam); A = Ativan (lorazepam); X = Xanax (alprazolam)
Indications (Uses):
V - anxiolytic, preoperative sedative, anticonvulsant.
A - anxiolytic, preoperative sedative.
X - anxiolytic, panic disorder.Equivalent Doses:
V - 5mg
A - 1mg
X - 0.5mgApproximate Half-life:
V - 100h
A - 10-20h
X - 12-15hOnset of Action
V - < 1h
A - 1-3h
X - 1-3hAre Metabolites Active?
V - yes
A - no
X - yesMetabolism:
V - oxidation
A - conjugation
X - oxidation
I think I will try the Xanax ER, although it is quite expensive (no generic). Keep me posted on how this is working for you!L Rae
poster:Lindsay Rae
thread:447040
URL: http://www.dr-bob.org/babble/20050124/msgs/447723.html