Posted by linkadge on November 30, 2004, at 14:31:56
In reply to Re: drug-induced illness... to Link, posted by ed_uk on November 30, 2004, at 11:41:56
I agree with the results but not the conclusion of the studies. Lithium is the most neuroprotective substance we have. I'm not sure what the mechanism of this might be but I can only make a proposition.
Perhaps in people who are predisposed to TD might have a irregulation in dopamine/glutamate that when unmedicated it beeing slowly compensated for
by the brain's own mecanisms. When a glutamate stabalizer is introduced, the brains own mechanisms become supressed and the TD surfaces full force.I've read some studies that show lithium can reduce neuroleptic induced alterations in limbic and substantia niagra (sp.) glutamate activity.
A lot of schitsoprenics drink coffee which might ofset some of the neurolecptic induced movement disorders. Caffiene is protective in a mouse model of PD and TD.
Linkadge
poster:linkadge
thread:422246
URL: http://www.dr-bob.org/babble/20041128/msgs/422438.html