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Re: Stimulants as an Antidepressant » fayeroe

Posted by King Vultan on July 29, 2004, at 12:53:26

In reply to Re: Stimulants as an Antidepressant » King Vultan, posted by fayeroe on July 29, 2004, at 9:42:52

> 20mg of prozac and 50mg of elavil. prozac in the a.m. and elavil at night. all i think about is eating. i've never, ever been like this. i'm just five feet tall and i'm miserable with the extra pounds...both meds are the generic variety because they are so much cheaper than the originals. any info is much, much appreciated, Todd.....thanks, pat


My opinion is that this particular combination is not likely to be all that dangerous, but if I were the doctor, I would be checking your blood plasma level of the amitriptyline just to be certain of where you're at. What has likely happened, however, is that the blood plasma level of the amitriptyline has been boosted to a level similar to what you would see if you were taking 100-300 mg of this drug by itself. In other words, you are probably somewhere around a full therapeutic dose, with the associated side effects.

Amitriptyline is a relatively powerful antihistamine, which is associated with appetite increase and weight gain. If it were me, I would ask the doctor to alter the drug combo to one that would tend to cause less weight gain. It's surprising how many doctors are not sensitive to the distress this side effect can cause their patients.

Todd


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