Posted by SLS on July 6, 2004, at 16:05:58
In reply to Re: vegetative depression, nortriptyline dosage » SLS, posted by zeugma on July 6, 2004, at 15:43:57
Hi Zeugma.
> II began getting hypnagogic/hypnopompic hallucinations (dreamlike states mixed with features of waking consciousness) at the age of 23. At times I have the 'dream within a dream' (false awakening) experience and when I actually wake up, less than 5 minutes have gone by on the clock. As far as I know, the images formed during stage 1 sleep do not have this quality at all; it aapears to be confined to REM states.
> These hallucinations/premature REM events are blocked to varying extents by nortriptyline, buspirone, and Strattera, but not by clonazepam, and of these four medications, only clonazepam is not a strong REM inhibitor.
> When I took Strattera at the same time as clonazepam, and then fell asleep, I did not experience these states, consistent with Strattera's rapid absorption and powerful REM-suppressing effect (for more on this see http://www.sro.org/pdf/863.pdf, which used Strattera's cousin, nisoxetine). When I fell asleep after taking Provigil, I experienced extremely vivid dreams and did not feel rested at all.
Have you developed any tolerance to the REM inhibiting effects of these drugs?When I first took tricyclics and MAOIs, they had a profound effect in reducing or completely abolishing dreaming and presumably REM sleep in me. Upon discontinuation of these drugs, I would experience an intense REM rebound where I would experience the type of waking dreams you described. These things don't happen to me anymore. I wish they did.
- Scott
poster:SLS
thread:363009
URL: http://www.dr-bob.org/babble/20040704/msgs/363526.html