Posted by Sad Panda on June 12, 2004, at 3:26:49
In reply to Re: 5-HT2A vs. 5-HT2C followup, posted by King Vultan on June 11, 2004, at 19:08:54
>
> > Stahl in "Essential Psychopharmacology" says it's the 5-HT2A receptors. Unfortunately, I don't have the book with me today at work, and I can't remember exactly what he says about the 5-HT2C receptors. I will try to remember to look it up when I get home.
> >
>
>
> He says stimulating these receptors has these side effects:
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>
> 2A (limbic cortex) agitation, anxiety, panic
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> 2A (spinal cord) orgasm dysfunction
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> 2A (brain pleasure centers) loss of libido, apathy
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> 2A (brainstem sleep centers) sleep disturbance, myoclonus
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> 2A (basal ganglia) changes in motor movements, restlessness
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> 2C (limbic cortex) agitation, anxiety, panic
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> 2C (location not specified) reduced appetite
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> 3 (hypothalamus) nausea
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> 3 (brainstem) vomiting
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> 3 & 4 (gastrointestinal tract) increased bowel motility, cramps, diarrhea
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>
> Todd
>
>Hard to argue against Stahl. :)
> 2C (location not specified) reduced appetite
Not hard to imagine why Remeron makes people fat, H1 & 5-HT2C antagonism both make people hungry. Remeron reduces my appetite, the happier I am, the less binge eating I do.
Cheers,
Panda.
poster:Sad Panda
thread:355574
URL: http://www.dr-bob.org/babble/20040608/msgs/355967.html