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Re: Sucess stories on Nardil for SP?? HELP! » ace

Posted by Shanti1 on May 28, 2004, at 8:36:15

In reply to Re: Sucess stories on Nardil for SP?? HELP! » Shanti1, posted by ace on May 27, 2004, at 22:46:36

Ace,

I always look forward to hearing from you. It's become a habit for me to check this forum to get a posting from you and you are always right there for me. Thanks!

> > 2) What category is Nardil? I am planning on having a baby and found little research in this area.
>
> Category? It is a Monoamine Oxidase Inhibitor. I can do some research on the pregnancy bit- would u like me too?

Yeah, I know that it's a MAO Inhibitor, but I wanted to know what category it was for pregnancy, sorry I wasn't specific on that. I think it's a class C. But am not too sure. That would be so great if you could find any info in relation to pregnancy!

Also, would you like me to explain how it works? I will explain it in easy terms so you understand. I'm assuming you don't at the moment. I could be wrong!

I know it works by inhibiting, thus eventually increasing levels of NE, Dopamine, Serotonin and GABA. Am i right?
>
>
> > 3) Do you know the half-life of Nardil?
>
> Very short. 2-3 hours. But THE HALF LIFE OF NARDIL DOES NOT CORRELATE WITH THE DURATION OF IT'S THERAPEUTIC ACTION. Enzyme inhibition continues longer than the half life.
>
I can't believe it's that short. Even my pharmicist couldn't find that info for me. So is that why in the leafleet along w/the Nardil it says to dose 3x a day at 15mg? My psych. doc is starting me at 7.5 mg a day. I know you said to ramp up to 60 mg ASAP. So I will see how it goes. Since the half-life is so short, I should feel the side effects (hopefully not more anxiety) right away. If no side effects--then maybe I will increase the dose.

More questions:

1) Do you know the peak onset of Nardil? I mean when does it hit the brain? Since it's half-life is SO short I am assuming it's onset is rather quick 1-2 hours at most.

2) Before Nardil did you try any of the SSRI's and if so what were your experiences?

3) When you were ramping up your Nardil dose did you divide your doses or did you take it all in the morning?


Last night I went to bed thinking what you told me "Nardil is on my side", Nardil is on my side". It comforted me greatly to know that if it helped you it can help me too.

thanks for all your support and time,

Shanti



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