Posted by SLS on January 17, 2004, at 11:14:49
In reply to Re: Depression moclobemide narcolepsy, posted by MARKED on January 17, 2004, at 9:39:25
> What is your situation with what medications, and treatments you are (or have) used ?? And what seems to be the major frustration now while being on moclobemide??I became severely depressed at age 17. At age 22, I was diagnosed as having unipolar depression at Columbia Presbyterian Hospital. I began with the tricyclics and MAOIs. Prozac hadn't been approved yet. At age 27, I was successfully treated using a combination of Parnate + desipramine. Unfortunately, I became severely manic after experiencing 6 months of remission. It was my first manic episode and it seemed to be medication induced. Because of this reaction, I was later diagnosed as having bipolar depression. My doctor at the time elected to have me discontinue the antidepressants and added lithium. I relapsed into depression two months later. The combination treatment did not work subsequently, and have been stuck in the depressive state ever since.
Right now, I am taking:
Lamictal 300mg
imipramine 300mg
Zoloft 200mg
lithium 300mg
Abilify 10mgI just added the lithium. Although I have tied it in the past at dosages up to 1200mg, I have never used it as an augmentor to Lamactal or Zoloft. As an augmentor, I would like to keep the dosage below 600mg
I tried moclobemide seven years ago. It made me unimaginably worse.
With most people, moclobemide produces an improvement during the first week and at low dosages < 300mg. Thereafter, it takes higher and higher dosages to maintain the antidepressant effect. Dosages as high 1200mg are sometimes necessary. This is a common scenario, and I don't think the drug is used as a first-line treatment.
Best wishes,
Scott
poster:SLS
thread:281113
URL: http://www.dr-bob.org/babble/20040114/msgs/301988.html