Posted by btnd on August 25, 2003, at 1:48:31
In reply to Prevention of long-term negative effects?, posted by Ame Sans Vie on August 24, 2003, at 6:28:48
> ...For example, long-term use of amphetamines I believe could lead to dopaminergic and noradrenergic inadequacy (correct me if I'm wrong on any of this). And Dexedrine is really the only one I'm concerned about, actually.
>
> ...Anyway, does anyone have any ideas of anything I could take (over-the-counter preferably, but any and all suggestions are welcome) that would decrease these hypothetical risks? For example, could Eldepryl be of benefit? Phenylalanine?
I will soon start pretty much the same regime (Klonopin, Xanax normal or SR, Ultram, Dexedrine,Xyrem) so I was researching this topic too (mainly Dexedrine long-term neuro-degeneration). IMO When it comes to supplements anti-oxidants should be of use with every type of amphetamine - lipoic acid, green tea, vit.E, grape seed extract.
Eldepryl/Deprenyl would also be a good idea, since selegiline increases dopamine levels.
I also think that my 2 nightly Xyrem doses are beneficial, when it comes to Dexedrine usage - because Xyrem (GHB) increases dopamine in every part of the brain pretty significantly.I will also use andrewB's method to prevent amphetamine tolerance and eliminate any potential damage - take Memantine or Acamprosate. Both are NDMA antagonists and prevent amphetamine tolerance.
And I will still use Enada NADH at low level during the week, since it increases dopamine transmission via different mechanism than other meds.
Take care,
Brad
poster:btnd
thread:253550
URL: http://www.dr-bob.org/babble/20030823/msgs/253775.html