Posted by Larry Hoover on August 1, 2003, at 15:42:40
In reply to Re: stimulants: tyrosine, phenylalanine, dexedrine, posted by andys on August 1, 2003, at 11:19:50
> Lar,
> I was so pleased that you responded, since your past postings have shown real expertise on the subject. I'm in a pretty depressive period right now, so my brain isn't working too well. So it will take some time to digest your response, and make an intelligent response.That's kewl.
> In the meantime, do you feel NADH has a place in this equation? (in that it increases L-dopa in the body AND the brain), so is possibly unaffected by the mentioned bottleneck.
NADH is like putting new batteries in a flashlight that had been quite dim. It's the Energizer Bunny for energy production. It happens to directly promote a lot of enzymatic processes, including, apparently, the conversion of tyrosine to L-dopa.
> The natural question that follows is: what would you consider the ideal regimen for increasing catecholemine supplements, for anergic depression? (I'm currently on 500 mg. tyrosine, but reduced to 5 mg. NADH, because of growing anxiety and insomnia).
Are you taking other B-vitamins? You need to make sure you take a B-complex. You'll deplete other B's a faster rate because NADH accelerates the processes that use them up. You may also recall that both Ron Hill and I have noticed that TMG helps "smooth out" the anxiety/irritability arising from NADH.
> Interestingly, these side effects started when I DROPPED phenylalanine (I theorized that tyrosine by itself was having more effect, without phenylalanine).
You are at risk of committing an error in logic, here. If you think about scientific research, everything comes down to statistical significance, which is nothing more than an estimate of the risk of coincidental correlation. Coincidental correlation is the possibility that two things appear to be related, but aren't in fact related at all. They just happened by coincidence. Drawing a conclusion from coincidental correlation is an error in logic known as "post hoc, ergo propter hoc"...literally, "after this, therefore because of this". Just because a particular event follows a specified manipulation does not mean the manipulation caused the event. It could have been a chance happening.
So, you can easily test the relationship by restarting phenylalanine (while keeping the other supplements constant), and see what it does for you/to you. Then stop it again. If your symptoms seem to alternate with that series of manipulations, you've got pretty good evidence for what phenylaline does in your body.
> As another side note, I just restarted Cytomel (T3 thyroid), after reading an article about the interactions of thyroid and catecholemines, hoping I would respond better to cytomel, now that i'm on catecholemine supplements.
I'll look into that.
Lar
poster:Larry Hoover
thread:246486
URL: http://www.dr-bob.org/babble/20030728/msgs/247412.html