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Re: Oversedation from Zyprexa, will Cytomel help? » JohnL

Posted by wingedcat on February 28, 2003, at 19:34:22

In reply to Re: Oversedation from Zyprexa, will Cytomel help?, posted by JohnL on February 28, 2003, at 5:10:26

> Zyprexa sedation is usually most significant in the first week or so. It will likely subside.
>
> I think you are doing the right thing by considering 2.5mg. Just cut the pill. The halves don't have to be exact.
>
> I take Zyprexa and I'm one of those who believes it is a supermed. I started at 2.5mg for about a month, it seemed to wear off, so I went to 5.0mg and that's where I have stayed.
>
> Starting at 5.0mg I think is a mistake. Another mistake is to take the dose at bedtime. A better way is to take it around 5:00 to 6:00 pm. This way the sedation is not as bad the next morning. If you take it at bedtime, that is too late, and too much of the sedation will still linger the next morning.
>
> In any case, the sedation should subside rather quickly. Lowering the dose and taking it earlier in the day should help a lot.
----------------------


I wouldn't have thought of Zyprexa on my own, but I think it was wise of my doc to put me on it. I hesitate to tell the doctors some of what goes on in my head because it scares me but I think he could tell by the way I was hesitating on his questions. I get not euphorically manic, but mixed dysphorically manic... trouble controlling my temper and impulses, 500 people chattering in my head at once. I tried taking only 2.5 mg before bed last night and I felt better... still sluggish when I woke up but at least I wasn't stumbling and slurring. My head is QUIET. It's a nice, but unusual change.

Tonight I will do your suggestion and take it a little earlier, when I start the process of winding down my day.

I hope it won't affect my concentration too much. As this is a dopamine antagonist, you'd think that would make my concentration horrible, right? But it perhaps only acts that way in the limbic (emotional) system, without affecting the dopamine in the cerebral cortex as much. I'll have to research that more. The dopamine and serotonin subreceptors get a little complex.

Thank you so much for your response!


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