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Re: Seek and yee shall find in medline/pubmed » katekite

Posted by JonW on June 5, 2002, at 13:20:50

In reply to Seek and yee shall find in medline/pubmed » JonW, posted by katekite on June 4, 2002, at 22:09:07

Hi Kate,

I'm certainly waiting for the day anti-depressants work like Advil, but aren't we all? Medline is a great resource, and I agree completely with what you said. You can follow any thought pattern like "...this drug affects this receptor in this way which had such and such effect on me so I wonder if this disorder has anything to do with this receptor then..." I've come to the conclusion that everything has to do with everything but there's obviously more to it than that. And my brain definitely seems to need serotonergic drugs, but I also like dopaminergic or noradrenergic drugs but I'm not sure which. Maybe I need it all (my brain is selfish :)), and being on Nardil will suit me well!

Fingers crossed,
Jon

> I totally agree... I can't argue with the idea the ssris take 6 weeks to work but raise serotonin on day one.
>
> What's weird to me though, is how close it actually has come, for me, if I oversimplify. Like if I say: I've got almost but not quite enough serotonin, that I have too much norepinephrine, and not enough dopamine -- all the drugs I've taken make sense with regard to their most recognized mechanisms and fall neatly into categories. It is so tempting to believe in the oversimplified version.
>
> One thing that trips me up is how easy it is to find an explanation if I specifically look for it. For example, if I type in search words "empathy" and "serotonin" I will be almost certain to find at least one person that thinks empathy comes solely from serotonin. Or that serotonin is anti-empathy. I'll find something. Seek and yee shall find in pubmed. Even if its not really true. It is very difficult to find out if what you're reading is an accepted theory, a wormy hypothesis, or the lifework of a crackpot, given that in pubmed, everything sounds very scientific.
>
> So -- buyer beware.
>
> kate


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